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News and Trends 12 Nov 2019

First Results Out for Off-the-Shelf CAR-T Therapy in Solid Tumors

The Belgian company Celyad has released the first interim clinical efficacy data for an off-the-shelf CAR T-cell immunotherapy in solid tumors. The interim results come from an ongoing phase I trial in patients with colorectal cancer. Of the 12 patients given Celyad’s CAR T-cell immunotherapy so far, six have seen their tumors shrink. The therapy […]

November 12, 2019 - 2 minutesmins - By Jonathan Smith

cancer treatments personalized technology

In Depth 15 Oct 2019

Four New Technologies That Will Change Cancer Treatment

New approaches to tame the immune system in the fight against cancer are getting us closer to a future where cancer becomes a curable disease. Personalized vaccines, cell therapy, gene editing and microbiome treatments are four technologies that will change the way cancer is treated. Curing cancer is certainly one of the big challenges of […]

October 15, 2019 - 9 minutesmins - By Clara Rodríguez Fernández

News and Trends 27 Feb 2019

UK Biotech Gets Huge Grant to Launch Off-the-Shelf CAR-T Cancer Therapy to Clinic

The UK biotech Cell Medica has received a €7.6M ($8.7M) grant from the Cancer Prevention and Research Institute of Texas to advance an off-the-shelf CAR-T cell therapy that can work not only in blood cancer but also in solid tumors. The funding will help the company to develop a special type of CAR-T cell therapy […]

February 27, 2019 - 3 minutesmins - By Jonathan Smith

Best in Biotech 31 Dec 2018

European Biotech’s Biggest News of 2018

With this year coming to a close, it’s now time to look back at the biggest biotech news stories of 2018 in Europe, which include CRISPR-Cas9 controversy, big financial deals, and spider silk airplanes. The year 2018 brought a lot of change to the biotech industry in Europe, with clinical trials, approvals and Brexit […]

December 31, 2018 - 12 minutesmins - By Jonathan Smith

News and Trends 14 Nov 2018

CAR-T Promise for Patients with Solid Tumors

A new CAR-T cancer therapy from the Belgian company Celyad has shown early positive results against solid tumors in two Phase I trials, including one trial that did not include add-on chemotherapy. In one ongoing Phase I trial, Celyad’s CAR-T therapy, combined with chemotherapy, successfully shrank tumors in three enrolled patients with aggressive colorectal cancer. One […]

November 14, 2018 - 3 minutesmins - By Jonathan Smith

News and Trends 24 Jul 2018

Celyad’s Donor Cell CAR-T Therapy Gets Closer to the Clinic

Celyad has received FDA approval to start clinical trials for its CAR-T cell therapy, which is engineered to avoid side effects associated with using donor cells for this kind of treatment. The Belgian biotech has been cleared to test its CAR-T cell therapy, made from donor cells, in patients with unresectable colorectal cancer in combination […]

July 24, 2018 - 2 minutesmins - By Alexander Burik

News and Trends 22 Jun 2018

Next-Generation CAR-T Company Raises €130M on NASDAQ IPO

London-based Autolus has made its debut on the NASDAQ raising funds to boost the development of a next generation of CAR-T cell therapy for cancer. Founded in 2014 as a spin-out from University College London, Autolus has been taking great strides to develop its CAR-T technology. In less than four years, the company managed to raise nearly €150M […]

June 22, 2018 - 2 minutesmins - By Clara Rodríguez Fernández

News and Trends 13 Jun 2018

French Biotech Develops a New Generation of Safer CAR-T Cells

Cellectis is developing a new type of chimeric antigen receptor that could improve the production and safety of CAR-T cell therapies generated from both patient and donor cells. Cellectis, a French biotech focused on developing CAR-T therapies from donor cells, has published a study in the journal Scientific Reports describing technological advances that could improve the […]

June 13, 2018 - 2 minutesmins - By Alexander Burik

Interview 13 Jun 2018

CAR-T Brings Hope for Cancer Patients, But Challenges Lie Ahead

CAR-T cell therapy has been able to effectively treat cancer in some patients for whom all other treatment options were exhausted. However, the technology still has a long road ahead before becoming a widespread treatment option. Philip spoke to Christian Homsy, CEO of Celyad, at our Refresh Meetup in Brussels about the challenges CAR-T cell […]

June 13, 2018 - 5 minutesmins - By Alexander Burik

News and Trends 23 May 2018

Belgian Biotech Gets a €46M Boost to Keep up in the CAR-T Race

Update (23/05/2018): Investors have fully subscribed Celyad’s global offering of shares on NASDAQ and Euronext Paris, making the company raise a total of $54.4M (€46M) to support the development of its CAR-T technology. 18/05/2018 Celyad has raised €40M ($47M) in a global offering, which could help the company keep up with large competitors amidst recent large […]

May 23, 2018 - 2 minutesmins - By Alexander Burik

News and Trends 26 Apr 2018

Israeli Cell Therapy for Muscle Injury Will Start Phase III Trial in US

Pluristem Therapeutics will start a Phase III trial this year in the US for its pioneering cell therapy that uses placenta cells to restore muscle injuries. Pluristem Therapeutics, an Israeli biotech and world-leader in cell therapies, has received a green light from the FDA to start a Phase III study in the US. The trial will test […]

April 26, 2018 - 2 minutesmins - By Alexander Burik

News and Trends 23 Apr 2018

The First CAR-T Therapy Is Not Living Up to Commercial Expectations

Novartis’ Kymriah, the first approved CAR-T therapy worldwide, has performed far below sales expectations in the last quarter. The news highlights the challenges CAR-T therapies still face before becoming a commercially viable treatment option. CAR-T therapy has shown impressive results treating the cancer of patients for which all other treatments fail. One would expect this […]

April 23, 2018 - 3 minutesmins - By Editorial Team

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