Liver disease Archives

News and Trends 27 Mar 2019

Genfit Gets Ready to Launch Drug for Untreated Liver Disease Raising €120M

After some big failures from its top competitors earlier this year, French company Genfit has done an IPO to prepare the launch of its drug for NASH, a chronic liver disease for which there is currently no treatment. Today, Genfit has started trading on Nasdaq. Together with issuing new shares in its existing Euronext Paris […]

March 27, 2019 - 3 minutesmins - By Clara Rodríguez Fernández

autoimmune liver disease Genkyotex organ

News and Trends 7 Nov 2018

Solid Phase II Performance for French Autoimmune Liver Disease Drug

Genkyotex’s small molecule therapy had encouraging short-term effects on patients with the autoimmune liver disease primary biliary cholangitis in a Phase II trial. Over six weeks, the drug reduced the blood levels of a liver disease biomarker molecule by up to 23% in 92 participants. In patients with late-stage disease, who have few treatments available, […]

November 7, 2018 - 2 minutesmins - By Jonathan Smith

News and Trends 20 Sep 2018

RNA Therapy Shows Promise for Treating Liver Cancer

British biotech MiNA Therapeutics’ innovative RNA treatment may enhance liver cancer patients’ response to standard cancer therapies, suggest early results from a Phase I/IIa clinical trial. When they received the biotech’s small activating RNA (saRNA) treatment, two patients showed complete responses after being given the cancer treatment sorafenib and one showed a partial response to […]

September 20, 2018 - 2 minutesmins - By Jonathan Smith

News and Trends 5 Jun 2018

French Biotech Raises €40M to Fight Hepatitis B and NASH

Enyo Pharma has completed a Series B financing round to start Phase II trials by the end of this year testing its lead compound in two different forms of liver disease. Enyo Pharma, based in Lyon, has raised €40M from OrbiMed and other investors to start two Phase II trials testing its lead drug candidate […]

June 5, 2018 - 2 minutesmins - By Alexander Burik

Alexion Pharmaceutical Wilson Therapeutics 2

News and Trends 11 Apr 2018

Alexion Acquires Swedish Treatment for Wilson’s Disease

Alexion Pharmaceutical intends to buy Wilson Therapeutics for nearly $1Bn. Wilson is developing a first-in-class treatment for Wilson’s disease, a rare disorder that can lead to severe liver and brain damage. Alexion Pharmaceuticals, one of the most successful companies in rare diseases and known for selling one of the most expensive drugs in the world, […]

April 11, 2018 - 2 minutesmins - By Alexander Burik

News and Trends 27 Nov 2017

NASH Leader Signs Up for EU Project to Fight Deadly Liver Disease

Update 27/11/17: Genfit, the leader in the fight against NASH, has joined the LITMUS study. The company will share its experience and resources with the EU collaboration by contributing samples from its RESOLVE-IT clinical study. Genfit will co-lead two projects in patient recruitment and specialized biomarker assays, focusing on genetics and miRNA. Originally published: 23/11/17 […]

November 27, 2017 - 3 minutesmins - By Alex Dale

News and Trends 8 Nov 2017

German Pharma and Biotech Gang Up on NASH in an Exciting Collaboration

Boehringer Ingelheim’s fight against liver disease is taking shape, having agreed on a partnership with RNA pioneer MiNA Therapeutics to fight NASH. British biotech, MiNA Therapeutics, has announced a partnership with pharma giant Boehringer Ingelheim to focus on developing compounds to treat fibrotic liver diseases like Non-Alcoholic SteatoHepatitis (NASH). Bringing MiNA on board has given Boehringer Ingelheim access to […]

November 8, 2017 - 3 minutesmins - By Alex Dale

News and Trends 29 Jun 2017

This French Biotech is Starting Two New Trials to Treat Kidney and Liver Fibrosis

Genkyotex has announced a new Phase II trial in diabetic kidney disease and patient enrolment in another Phase II study for PBC. Genkyotex is not giving up after its lead candidate, GKT831, failed to meet the primary endpoint in a Phase II trial in patients with type 2 diabetes and kidney disease. The French biotech has […]

June 29, 2017 - 2 minutesmins - By Clara Rodríguez Fernández

News and Trends 19 Jun 2017

This Company Uses the Human Microbiome to Discover New Disease Mechanisms

A whole new avenue to human health and disease could soon be accessible, thanks to the human tissue microbiome. Vaiomer has found a way to make it possible! Has anyone else ever been unsettled by the idea that the human body hosts about 10 times more microbes than human cells? Although this might seem an […]

June 19, 2017 - 5 minutesmins - By External Contributor

News and Trends 3 May 2017

French Biotech gets a Second Opportunity to Fight Liver Fibrosis

Genkyotex, a French biotech with an eye on NASH, has received FDA approval to initiate a Phase II trial in primary biliary cholangitis. Genkyotex’s lead candidate, GKT831, failed to prove its efficacy in a Phase II trial for diabetic nephropathy a couple of years ago. Now, the company is taking a second shot by targeting liver […]

May 3, 2017 - 3 minutesmins - By Clara Rodríguez Fernández

News and Trends 18 Jan 2017

Evotec launches New Biotech to tackle the Most Deadly Diseases

Evotec has backed the foundation of Fibrocor, a Canadian company that will work on fibrosis, the underlying cause of some of the most deadly diseases. Fibrocor was launched yesterday in Toronto with €2M (CDN 2.8M) from the successful German biotech CRO Evotec and the Canadian non-profit MaRS Innovation. Evotec will provide all drug discovery activities […]

January 18, 2017 - 2 minutesmins - By Clara Rodríguez Fernández

News and Trends 9 Jan 2017

Top European VC and CRO fund Young Metabolic Disease Biotech

Eternygen has received €8M in a Series A round led by Epidarex Capital that will be used to advance its pipeline in collaboration with Evotec. Eternygen is a young biotech in Berlin focusing on the treatment of metabolic diseases. The company has now raised €8M in Series A, led by Scottish biotech VC Epidarex Capital. Among the […]

January 9, 2017 - 2 minutesmins - By Clara Rodríguez Fernández

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