Jonathan Smith, Author at Labiotech.eu

About

Reporter for Labiotech. I hail from the UK. I was born in Bristol, studied Neuroscience in the University of Bristol, and trained mice in Eisai, Hertfordshire, for one year. I then tickled locusts for my Ph.D. at the University of Leicester, before eventually ending up here!
Out of the office, I travel, play video games and board games, drink beer and play the piano.

Articles by Jonathan Smith

mallinckrodt regenerative medicine skin graft bioprinting skin

News and Trends 14 Aug 2019

Engineered Skin Shows Potential to Treat Burns in Phase I

Engineered skin tissue, developed as a regenerative medicine by the UK-US pharma company Mallinckrodt, has reduced the need for skin grafts in burns victims in a phase Ib trial. The phase I trial tested Mallinckrodt’s engineered skin treatment in 29 patients suffering from deep second degree burns. Patients with these burns have damage to the […]

August 14, 2019 - 2 minutesmins - By Jonathan Smith

News and Trends 13 Aug 2019

AskBio Acquires Scottish Biotech to Make Gene Therapies More Precise

The US company AskBio has acquired the Edinburgh-based Synpromics to pool their gene therapy technologies and produce inducible gene therapies that target particular organs or cells. AskBio specializes in developing viral vectors that carry gene therapies into cells, such as adeno-associated virus, whereas Synpromics develops DNA sequences called promoters that drive the expression of gene […]

August 13, 2019 - 2 minutesmins - By Jonathan Smith

News and Trends 12 Aug 2019

Manufacturing Delays Set Back Autolus’ CAR-T Programs by Five Months

The UK biotech Autolus’ shares have slumped as construction delays from a new manufacturing site have pushed back its CAR-T cell immunotherapy programs. Autolus is developing treatments for blood cancer that involve engineering patients’ own immune cells to kill cancer cells, known as autologous CAR-T cell immunotherapies. Earlier this year, Autolus licensed a new manufacturing […]

August 12, 2019 - 2 minutesmins - By Jonathan Smith

water pollution solutions pharem biotech sweden uppsala

Startup Scout 9 Aug 2019

This Biotech Cleans up Drugs from Sewage Using Enzymes

We’re visiting Uppsala, Sweden, this week. This city is home to Pharem Biotech, a company developing enzymes to break down drug residues contaminating wastewater. Mission: To remove drug residue from sewage water by developing enzymes that are modified to be 200 times more effective than natural enzymes. This technology could reduce the ecological and health […]

August 9, 2019 - 3 minutesmins - By Jonathan Smith

News and Trends 7 Aug 2019

Late-Stage Clinical Trial Troubles for Dry Eye Disease Drug

A drug developed by the UK company Topivert Pharma has failed to reduce eyeball grittiness sensations in patients with dry eye disease in a phase II/III trial. The trial tested Topivert’s small molecule drug given as eyedrops to 202 patients suffering from dry eye disease, a condition where not enough tears are produced to lubricate […]

August 7, 2019 - 2 minutesmins - By Jonathan Smith

adc therapeutics genomics sophia genetics blood cancer

News and Trends 6 Aug 2019

ADC Therapeutics and SOPHiA Genetics Team Up to Personalize Cancer Treatment

Two companies based in Lausanne, Switzerland — ADC Therapeutics and the genomics company SOPHiA Genetics — have signed a deal to identify patients most likely to respond to a blood cancer drug. ADC Therapeutics will send SOPHiA Genetics blood samples collected from an ongoing phase II trial. The trial is testing a treatment for patients […]

August 6, 2019 - 2 minutesmins - By Jonathan Smith

More News! 5 Aug 2019

Phase II Promise for Inhaled Chronic Lung Disease Treatment

A first-in-class inhaled drug developed by the UK biotech Verona Pharma improved lung function in a phase II trial treating the lung condition chronic obstructive pulmonary disease. The 37 patients in the trial had chronic obstructive pulmonary disease (COPD), a common lung condition that involves a tightening of the lung airways and breathlessness. Verona Pharma […]

August 5, 2019 - 2 minutesmins - By Jonathan Smith

oncolytic virus cancer treatment transgene sillajen

News and Trends 2 Aug 2019

Oncolytic Virus for Liver Cancer Ruled Futile in Phase III

A phase III trial testing an oncolytic virus treatment for liver cancer, developed by the French biotech Transgene, has been discontinued after interim analyses concluded that the treatment was unlikely to succeed. Originally expected to finish in 2020, the phase III trial tested the oncolytic virus treatment Pexa-Vec in patients with the liver cancer hepatocellular […]

August 2, 2019 - 2 minutesmins - By Jonathan Smith

acute respiratory distress syndrome pantherna berlin inflammatory disease

Startup Scout 2 Aug 2019

This Biotech Uses Messenger RNA to Treat Lethal Lung Inflammation

Based close to Berlin, Germany, the biotech startup Pantherna Therapeutics is developing a messenger RNA drug to treat a life-threatening lung condition that requires mechanical ventilation. Mission: To develop a messenger RNA (mRNA) drug to treat acute respiratory distress syndrome, an inflammatory lung reaction that kills up to half of patients with the condition. Acute […]

August 2, 2019 - 4 minutesmins - By Jonathan Smith

atlantic healthcare pouchitis inflammatory bowel disease

More News! 1 Aug 2019

Atlantic Healthcare’s Inflammatory Bowel Disease RNA Drug Fails Phase III

Hopes of seeing an approved treatment for the inflammatory bowel condition pouchitis have been dashed as the UK company Atlantic Healthcare’s RNA drug has proved ineffective in a phase III trial. The trial tested Atlantic Healthcare’s RNA drug alicaforsen as a treatment for patients with pouchitis. Patients with this condition have their colon surgically replaced […]

August 1, 2019 - 2 minutesmins - By Jonathan Smith

inflammatory bowel disease treatment personalized medicine predictimmune

News and Trends 31 Jul 2019

British Biotech Raises €11M to Market Personalized Medicine Test

The UK biotech PredictImmune has raised €11M (£10M) in a Series B fundraising round to commercialize technology to predict the progress of inflammatory bowel disease in newly diagnosed patients. The funds will finance the global launch of PredictSURE IBD, a blood test that can identify patients with the most severe cases of inflammatory bowel disease, […]

July 31, 2019 - 3 minutesmins - By Jonathan Smith

News and Trends 31 Jul 2019

French Biotech’s Insulin Resistance Treatment Boosted by €67M Series A

The French company Alizé Pharma III has raised a Series A round of €67M to push two peptide drugs into phase I, including a drug treating rare genetic conditions causing insulin resistance. The money will advance Alizé Pharma III’s two preclinical drugs into clinical trials, with phase I trials expected to begin in 2020. One […]

July 31, 2019 - 2 minutesmins - By Jonathan Smith

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Jonathan Smith

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Articles by Jonathan Smith

Engineered Skin Shows Potential to Treat Burns in Phase I

AskBio Acquires Scottish Biotech to Make Gene Therapies More Precise

Manufacturing Delays Set Back Autolus’ CAR-T Programs by Five Months

This Biotech Cleans up Drugs from Sewage Using Enzymes

Late-Stage Clinical Trial Troubles for Dry Eye Disease Drug

ADC Therapeutics and SOPHiA Genetics Team Up to Personalize Cancer Treatment

Phase II Promise for Inhaled Chronic Lung Disease Treatment

Oncolytic Virus for Liver Cancer Ruled Futile in Phase III

This Biotech Uses Messenger RNA to Treat Lethal Lung Inflammation

Atlantic Healthcare’s Inflammatory Bowel Disease RNA Drug Fails Phase III

British Biotech Raises €11M to Market Personalized Medicine Test

French Biotech’s Insulin Resistance Treatment Boosted by €67M Series A

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Catalonia: A biotech hub going from strength to strength, with Barcelona at its core

Top biotech deals of February 2025

Grab your free report on 3D organoids and explore their future potential

These 7 biotechs are shaping the next generation of endometriosis care

Connect with decision-makers and researchers worldwide for collaborative opportunities

Subscribe to our newsletter

Advertise with us

Catalonia: A biotech hub going from strength to strength, with Barcelona at its core

Top biotech deals of February 2025

Grab your free report on 3D organoids and explore their future potential

These 7 biotechs are shaping the next generation of endometriosis care

Connect with decision-makers and researchers worldwide for collaborative opportunities

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Advertise with us

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