Eye Disease Archives

News and Trends 7 Aug 2019

Late-Stage Clinical Trial Troubles for Dry Eye Disease Drug

A drug developed by the UK company Topivert Pharma has failed to reduce eyeball grittiness sensations in patients with dry eye disease in a phase II/III trial. The trial tested Topivert’s small molecule drug given as eyedrops to 202 patients suffering from dry eye disease, a condition where not enough tears are produced to lubricate […]

August 7, 2019 - 2 minutesmins - By Jonathan Smith

chemical burns manchester cornea stem cells

News and Trends 3 Apr 2019

UK Scientists Activate Stem Cells to Heal Corneal Injuries

A group of researchers in the UK has developed a potential treatment for corneal injuries, such as those caused by chemical burns, by making surrounding tissue softer and letting stem cells regenerate damaged tissue. The cornea is a transparent tissue that is important for focusing light onto the retina and guarding entry into the eye. […]

April 3, 2019 - 2 minutesmins - By Jonathan Smith

pixium vision retinal implant dry age related macular degeneration

News and Trends 10 Jan 2019

This Retinal Implant Lets Visually-Impaired Patients See Patterns

An electronic chip from French company Pixium Vision, inserted behind the retina to treat age-related macular degeneration, has shown excellent results in a small clinical trial. The five patients in the feasibility study suffered from dry age-related macular degeneration, the most common cause of visual impairment in people over 65 in Europe. In this incurable […]

January 10, 2019 - 3 minutesmins - By Jonathan Smith

News and Trends 4 Jan 2019

Innovative Eye Disease Therapies Move Closer to the Clinic

Oculis has increased its series B fundraising round to CHF35M (€31M) to continue development of its pipeline of topical eye treatments for diseases such as diabetic macular edema. The company specializes in creating special nanoparticle formulations of drugs for treatment of various eye diseases to allow them to be applied directly to the eye as […]

January 4, 2019 - 2 minutesmins - By Helen Albert

News and Trends 26 Nov 2018

First Gene Therapy for Inherited Blindness Approved in Europe

Novartis has received approval for Luxturna, a gene therapy that can restore vision in people with a specific genetic mutation that causes progressive vision loss. The therapy is indicated for people with mutations in the two copies of a gene, called RPE65, that cause retinal cells to die over time, resulting in progressive loss of […]

November 26, 2018 - 2 minutesmins - By Clara Rodríguez Fernández

News and Trends 18 Sep 2018

Update: French Biotech Raises €22M for a Gene Therapy Trial in Retinitis Pigmentosa

Update (18/09/2018): Horama has increased the total raised in its Series B fundraising to €22.5M, with the Belgian fund V-Bio Ventures joining the team of investors backing the company. The funds will be mainly directed at developing Horama’s gene therapy for retinitis pigmentosa. Published on 08/10/2017 Horama has raised a second fundraising round that will support […]

September 18, 2018 - 2 minutesmins - By Clara Rodríguez Fernández

News and Trends 5 Sep 2018

RNA Therapy Improves Vision in Patients with Rare Genetic Blindness

Dutch company ProQR has released data from a Phase I/II trial showing its RNA therapy can improve the vision of people with a rare form of hereditary blindness. The clinical trial recruited 10 people with the rare disease Leber’s congenital amaurosis 10. Caused by mutations in a gene called CEP290, this condition leads to […]

September 5, 2018 - 2 minutesmins - By Clara Rodríguez Fernández

News and Trends 20 Jul 2018

Belgian Biotech Completes First Trial with New Drug for Diabetic Macular Edema

Belgian biotech ThromboGenics has conducted the first clinical trial of an antibody to treat one of the world’s leading causes of vision loss. Results from the Phase I/II trial demonstrate the safety and tolerability of a new kind of antibody treatment for diabetic macular edema. The trial focused on injecting the THR-317 antibody, which is directed against […]

July 20, 2018 - 2 minutesmins - By External Contributor

Retinitis pigmentosa gene therapy Horama

News and Trends 11 Jul 2018

Gene Therapy for Retinitis Pigmentosa Tested in Humans for the First Time

French biotech Horama has treated the first patients with a gene therapy for retinitis pigmentosa that could prevent the progressive loss of vision caused by this genetic condition. A Phase I/II trial with Horama’s gene therapy for retinitis pigmentosa is running at the Nantes University Hospital. The therapy is aimed at fixing genetic defects in a […]

July 11, 2018 - 3 minutesmins - By Clara Rodríguez Fernández

genesight gene therapy blindness placebo

News and Trends 4 Apr 2018

Placebo Beats a Gene Therapy for Blindness in a Phase 3 Trial

GenSight has demonstrated that its gene therapy for a rare disease causing blindness can significantly improve the vision of patients. But so does the placebo. GenSight Biologics has released the results of a Phase III clinical trial testing its gene therapy GS010 in patients suffering from Leber hereditary optic neuropathy (LHON), a rare mitochondrial disease […]

April 4, 2018 - 2 minutesmins - By Clara Rodríguez Fernández

News and Trends 13 Mar 2018

French Biotech Restores Vision in Humans with Subretinal Implant

Pixium Vision has successfully restored vision in three patients with age-related macular degeneration (AMD) using an implanted wireless device, offering significant improvements to their quality of life. Pixium Vision has restored vision in three patients with age-related macular degeneration (AMD), using a wireless microchip, named PRIMA, that is implanted under a patient’s retina. The technology marks a […]

March 13, 2018 - 3 minutesmins - By Alexander Burik

News and Trends 6 Mar 2018

Oxford Spin-out Moves Gene Therapy For Blindness Into Phase III Trial

Nightstar Therapeutics will begin the first Phase III trial for a gene therapy targeting choroideremia, a rare disorder leading to complete blindness. Nightstar will launch the first-ever Phase III trial testing a gene therapy for choroideremia, a genetic disorder characterized by night blindness and gradual loss of vision that eventually leads to complete blindness. The trial, STAR, […]

March 6, 2018 - 2 minutesmins - By Alexander Burik

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Eye Disease

Late-Stage Clinical Trial Troubles for Dry Eye Disease Drug

UK Scientists Activate Stem Cells to Heal Corneal Injuries

This Retinal Implant Lets Visually-Impaired Patients See Patterns

Innovative Eye Disease Therapies Move Closer to the Clinic

First Gene Therapy for Inherited Blindness Approved in Europe

Update: French Biotech Raises €22M for a Gene Therapy Trial in Retinitis Pigmentosa

RNA Therapy Improves Vision in Patients with Rare Genetic Blindness

Belgian Biotech Completes First Trial with New Drug for Diabetic Macular Edema

Gene Therapy for Retinitis Pigmentosa Tested in Humans for the First Time

Placebo Beats a Gene Therapy for Blindness in a Phase 3 Trial

French Biotech Restores Vision in Humans with Subretinal Implant

Oxford Spin-out Moves Gene Therapy For Blindness Into Phase III Trial

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Catalonia: A biotech hub going from strength to strength, with Barcelona at its core

Top biotech deals of February 2025

Grab your free report on 3D organoids and explore their future potential

These 7 biotechs are shaping the next generation of endometriosis care

Connect with decision-makers and researchers worldwide for collaborative opportunities

Subscribe to our newsletter

Advertise with us

Catalonia: A biotech hub going from strength to strength, with Barcelona at its core

Top biotech deals of February 2025

Grab your free report on 3D organoids and explore their future potential

These 7 biotechs are shaping the next generation of endometriosis care

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