On this week’s podcast we have a conversation with Jordi Mata-Fink, co-founder and chief executive officer of Gate Bioscience. Gate Bioscience is a U.S.-based biotechnology company creating a new class of medicines called Molecular Gates. Founded in 2021, Gate is emerging from stealth with a novel scientific platform and $60 million in Series A funding […]
Since they were discovered around three decades ago, molecular glues have come a very long way as a therapeutic option for several different disease areas, including cancer and neurodegenerative disorders. Now, there are a rising number of molecular glue companies hoping to show clinical success with their candidates. The term molecular glue refers to a […]
With around 7500 new cases reported in the U.K. alone every year, ovarian cancer may occur because of the inheritance of faulty genes like BRCA. Although the exact reason for cancer-causing genetic mutations is unknown – as with all other kinds of cancer – ovarian cancer research has shown that the risk increases with age, […]
All living cells contain proteins with different functions, depending on the type of cell. Researchers at the University of Gothenburg in Sweden have discovered a way to identify proteins even without looking at their structure. They say their method is faster, easier and more reliable than previous methods. Currently, the general view is that each […]
AI tools like ChatGPT are revolutionizing how the world generates text, images and code. In a similar way, machine learning algorithms and generative AI are upending traditional processes in life sciences and collapsing time frames in drug discovery and materials development. AlphaFold by DeepMind is probably the most well-known machine learning model in this space. […]
Protein degradation platforms have revolutionized drug discovery aimed at undruggable targets. Biopharmaceutical companies around the world have engaged in the protein degradation field, with the hope of leveraging the capabilities of these coumpounds to successfully design drugs to treat diseases like cancer and neurodegenerative disorders. The discovery of the ubiquitin and proteolysis – protein degradation […]
Avilar Therapeutics has raised additional funding with an expanded syndicate of new investors to support advancing a pipeline of first-in-class extracellular protein degraders. The new financing takes the company’s total to $75 million. The seed round had initial funding from Avilar’s founding investor, RA Capital Management, and now includes participation by new investors Sanofi Ventures, […]
An impressive crowd gathered at Chiesi Pharmaceutical Group yesterday (November 21) to mark the much-anticipated start of work at its Biotech Center of Excellence, bringing the future of medicine to Parma. Guests, which included Vice Minister of Business and Made in Italy, Valentino Valentini, joined to celebrate the start of the work on the building, […]