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News and Trends 18 May 2023

New epilepsy study could lead to new treatment options

The mechanisms underlying the pathogenesis of epilepsy, a neurological disorder characterized by excessive electrical activity in the brain, remain unknown. Now, using a novel radiotracer, researchers from Japan have been able to offer insight into the role of AMPAR trafficking in epileptogenesis. The radio tracer is [11C]K-2, the first technology to visualize and quantify α-amino-3-hydroxy-5-methyl-4-isoxazole […]

May 18, 2023 - 4 minutesmins - By Jim Cornall

News and Trends 18 May 2023

Sania Therapeutics launches to advance neural circuit dysfunction medicines

Sania Therapeutics, which develops genetic medicines for neural circuit dysfunction, has launched with the unveiling of its platforms at the American Society of Gene & Cell Therapy (ASGCT) conference. Sania Therapeutics’ approach combines the evolution of adeno-associated viruses (AAV) in human neural circuits, the fundamental components of the nervous system, and tuneable conditionally-activated ion channels. […]

May 18, 2023 - 2 minutesmins - By Jim Cornall

News and Trends 17 May 2023

Diagnosing inflammatory diseases with synthetic peptides

Common inflammatory disorders such as ulcerative colitis and Crohn’s disease can be diagnosed or monitored by measuring the protein calprotectin in stool samples, while serum levels of calprotectin could be used to monitor the inflammation status in rheumatoid arthritis. Calprotectin concentrations in patient samples are typically determined using antibodies that bind and detect the protein, […]

May 17, 2023 - 3 minutesmins - By Jim Cornall

News and Trends 17 May 2023

Scribe and Prevail to accelerate CRISPR-based genetic medicines for neurological and neuromuscular diseases

Scribe Therapeutics Inc., a company creating genetic medicines through its CRISPR by Design approach to genetic modification, has announced a strategic collaboration with Prevail Therapeutics, a wholly owned subsidiary of Eli Lilly and Company. The deal gives Prevail exclusive rights to Scribe Therapeutics’ CRISPR X-Editing (XE) technologies for the development of in vivo therapies directed […]

May 17, 2023 - 3 minutesmins - By Jim Cornall

News and Trends 16 May 2023

LabGenius looks to create molecules with huge increase in tumor killing ability

LabGenius, which uses machine learning (ML) for antibody discovery, has presented data in a poster presentation at the Protein Engineering and Biotherapeutics (PEGS) annual meeting. The data were from LabGenius’ T-cell engager (TCE) lead optimization platform, which delivered highly potent and efficacious single-domain antibodies with best-in-class killing selectivity. Optimizing antibody therapeutics across multiple properties is […]

May 16, 2023 - 3 minutesmins - By Jim Cornall

News and Trends 16 May 2023

Molsid developing rapid AMR test

Start-up biomed Molsid is developing the first rapid test to detect the potential presence of antimicrobial resistance (AMR) directly in primary clinical samples. ORSET Group and PULSALYS, the SATT in Lyon, extended financing to the company in March 2023. This was followed by the signing of an i-DEMO contract with the French investment bank bpiFrance. […]

May 16, 2023 - 3 minutesmins - By Jim Cornall

Osteopetrosis ADO2 radiopaedia case ID 8037

News and Trends 16 May 2023

SiSaf siRNA therapy gets FDA designations to treat autosomal dominant osteopetrosis

SiSaf Ltd, an RNA delivery and therapeutics company, has announced that SIS-101-ADO, its siRNA therapeutic for patients with autosomal dominant osteopetrosis Type 2 (ADO2), has been granted orphan drug designation by the U.S. FDA. Also, due to the serious manifestations of this rare skeletal disorder in children, SIS-101-ADO has been granted rare pediatric disease designation […]

May 16, 2023 - 3 minutesmins - By Jim Cornall

News and Trends 16 May 2023

Researchers’ mutation discovery offers new Alzheimer’s hope

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder affecting tens of millions of people worldwide, and it is the most common cause of dementia. Early-onset AD is typically associated with mutations in the genes APP, PSEN1, and PSEN2, leading to a more aggressive form of the disease with atypical symptoms. In contrast, the newly discovered […]

May 16, 2023 - 3 minutesmins - By Jim Cornall

News and Trends 15 May 2023

New menopause drug gets FDA approval

The U.S. Food and Drug Administration has approved Astellas Pharma’s Veozah (fezolinetant), an oral medication for the treatment of moderate to severe vasomotor symptoms, or hot flashes, caused by menopause. Astellas Pharma US, Inc.’s Veozah is the first neurokinin 3 (NK3) receptor antagonist approved by the FDA to treat moderate to severe hot flashes from […]

May 15, 2023 - 2 minutesmins - By Jim Cornall

News and Trends 15 May 2023

Alzheimer’s drugs could result from immune brain cell discovery

A recent study published in Nature Neuroscience indicates that, contrary to common belief, the immune cells of the brain, known as microglia, are not all the same. Researchers found that a unique microglial subset with unique features and function is important for establishing proper cognitive functions in mice. Evidence for such microglial subsets exists also […]

May 15, 2023 - 3 minutesmins - By Jim Cornall

News and Trends 12 May 2023

DiogenX raises €27.5M for “breakthrough” diabetes treatment

DiogenX, a biotech company focused on regenerating insulin-producing beta cells for the treatment of diabetes, has announced the successful completion of a €27.5 million ($30 million) Series A financing round. New investors Roche Venture Fund, Eli Lilly and Company and Omnes joined this round alongside existing investors Boehringer Ingelheim Venture Fund (BIVF), JDRF T1D Fund, […]

May 12, 2023 - 2 minutesmins - By Jim Cornall

News and Trends 12 May 2023

Achilles Therapeutics’ new platform identifies most potent T-cell antigens

Achilles Therapeutics plc says its newly-developed AI application, trained with proprietary real-world data, outperformed current AI and non-AI methods for neoantigen immunogenicity prediction in a recent analysis, enabling the identification of the most potent clonal neoantigens for personalized cancer therapies. Further details of the company’s AI-powered PELEUS bioinformatics platform are expected to be presented at […]

May 12, 2023 - 3 minutesmins - By Jim Cornall

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News and Trends

New epilepsy study could lead to new treatment options

Sania Therapeutics launches to advance neural circuit dysfunction medicines

Diagnosing inflammatory diseases with synthetic peptides

Scribe and Prevail to accelerate CRISPR-based genetic medicines for neurological and neuromuscular diseases

LabGenius looks to create molecules with huge increase in tumor killing ability

Molsid developing rapid AMR test

SiSaf siRNA therapy gets FDA designations to treat autosomal dominant osteopetrosis

Researchers’ mutation discovery offers new Alzheimer’s hope

New menopause drug gets FDA approval

Alzheimer’s drugs could result from immune brain cell discovery

DiogenX raises €27.5M for “breakthrough” diabetes treatment

Achilles Therapeutics’ new platform identifies most potent T-cell antigens

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Catalonia: A biotech hub going from strength to strength, with Barcelona at its core

Top biotech deals of February 2025

Grab your free report on 3D organoids and explore their future potential

These 7 biotechs are shaping the next generation of endometriosis care

Connect with decision-makers and researchers worldwide for collaborative opportunities

Subscribe to our newsletter

Advertise with us

Catalonia: A biotech hub going from strength to strength, with Barcelona at its core

Top biotech deals of February 2025

Grab your free report on 3D organoids and explore their future potential

These 7 biotechs are shaping the next generation of endometriosis care

Connect with decision-makers and researchers worldwide for collaborative opportunities

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